In Windows Tweaks

• Search
• Remember Folder View
• Messenger off
• Tooltips off
• Performance
• Registry hacks
• Disable XP auto update
• Slimming XP
• Disable Indexing
• Disable startup programs
• Change drive letters
• Keyboard shortcuts
• Services
• Speed up NTFS
• Speed up Outlook
• Tweak the Prefetch
• Slow network browsing
• Notification ballons off
• Remove Shared Folder
• Move Startup Folder
• Menu Show Delay
• Animated Windows

Notification ballons off

To Disable The Notification Area Balloon Tips:

Click Start, click Run, type regedit, and then press ENTER.
Navigate to the following subkey:
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced
Right-click the right pane, create a new DWORD value, and then name it EnableBalloonTips.
Double-click this new entry, and then give it a hexadecimal value of 0.
Quit Registry Editor. Log off Windows, and then log back on.

These steps disable all Notification Area balloon tips for this user. There is no way to disable balloon tips for specific programs only.